Rapid Analgesia for Prehospital Hip Disruption (RAPID): a feasibility study for a randomised controlled trial

Welsh Ambulance Services NHS Trust0 个研究点目标入组 71 人开始时间: 2015年11月11日最近更新: 2023年1月9日

试验速览

2017 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/28163926 protocol 2019 Results article in https://www.ncbi.nlm.nih.gov/pubmed/31210961 results (added 19/06/2019) 2019 Results article in https://pubmed.ncbi.nlm.nih.gov/30772863 results (added 30/03/2020) 2019 Results article in https://pubmed.ncbi.nlm.nih.gov/31862740/ results (added 04/01/2021) 2018 Other publications in https://pubmed.ncbi.nlm.nih.gov/30209073/ Use of scratchcards for allocation concealment (added 01/12/2022)

•1. Aged 18 years or over
•2. Patients who are assessed by a paramedic as having a hip fracture (paramedics will make this assessment by using a hip fracture diagnosis checklist tool)

•1. Patient refuses to participate
•2. Patient is combative
•3. Patient has an allergy to local anaesthetic
•4. Patient is receiving coagulopathy (use of warfarin, clopidogrel or ‘new’ anticoagulants)
•5. Patient has any other distracting injury (i.e. has pain in a different place, which would make taking pain scores for only the hip difficult)
•6. Patient has decreased level of consciousness (Glasgow Coma Scale score of less than 14)
•7. Patient is haemodynamically unstable
•8. Patient has neurovascular damage to the affected leg
•9. Patient has received previous femoral bypass surgery
•10. Patient has an infection at the site of insertion of the injection
•11. The paramedic is unable to palpate the femoral artery on the affected leg
•12. Patients who appear to have body mass of less than 50kg (A 50kg patient could safely be given 6ml/kg of 1% prilocaine. By only using 30ml of the local anaesthetic, we will have a margin of safety to avoid patients developing local anaesthetic toxicity).

发起方

Welsh Ambulance Services NHS Trust