Effects of probiotic administration in the elderly
Phase 1
- Conditions
- Dementia, unspecified
- Registration Number
- RBR-3dmq83
- Lead Sponsor
- niversidade Federal do Rio Grande do Norte
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Data analysis completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
To be 60 years or more; being institutionalized; obtain values between 10 and 24 in the Mini Mental State Examination (MMSE), to exclude individuals with very mild dementias and very severe dementias; be able to walk
Exclusion Criteria
-Be less than 60 years; not being institutionalized; obtain value less than 10 and greater than 24 in the Mini Mental State Examination (MMSE); not being able to walk
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Decrease of at least 10% in the concentration of some metabolites related to chronic subclinical inflammation, variation observed in the pre and post intervention measurements, verified using the Nuclear Magnetic Resonance method and analysis using Chenomx software.
- Secondary Outcome Measures
Name Time Method Cognitive assessment performed through the Mini mental state examination, Rey auditory-verbal learning test (RAVLT),<br> and Wechsler Adult Intelligence Scale - Revised (WAIS-R) have not, so far, had a significant difference between pre- and post-treatment. Analyzes are still being done.