Evaluation of cerebral microembolism related to left atrial ablation of paroxysmal atrial fibrillatio
- Conditions
- I48.10I63.4Cerebral infarction due to embolism of cerebral arteries
- Registration Number
- DRKS00003465
- Lead Sponsor
- niversitätsklinikum Regensburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 65
Inclusion Criteria
1. Patients with paroxysmal atrial fibrillation scheduled for pulmonary vein isolation (PVI alone, no additional ablation)
2. Provided written informed consent
Exclusion Criteria
1. Age <18 and >80 years
2. Prior Stroke
3. Dementia
4. Prior pulmonary vein isolation
5. Severe claustrophobia
6. Implanted pacemaker/ICD (no MRI possible)
7. Persistent atrial fibrillation
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Composite endpoint of cerebral microembolisms demonstrated by cerebral magnetic resonance imaging (the day before and two days and one month after the procedure), microembolisms recorded by transcranial doppler (during the procedure) and neuropsychological events measured by trail making test A, trail making test B, controlled oral word association test, block tapping test und Ruff 2&7 test (the day before and two days and one month after the procedure).
- Secondary Outcome Measures
Name Time Method Influence of periprocedural management and technical settings on the occurence of cerebral microembolisms