PC-300 Tea Effect on Triglyceride Levels
- Conditions
- Hypertriglyceridemia
- Interventions
- Dietary Supplement: PC-300 tea.
- Registration Number
- NCT03649269
- Lead Sponsor
- Ciprés Grupo Médico CGM SC
- Brief Summary
Herbal medicine represents an alternative for treating dyslipidemia. The aim of this project was to evaluate the PC-300 tea (Eryngium heterophyllum egelm + Amphipterygium adstringens) against hypertriglyceridemia.
Baseline samples of serum total cholesterol and triglycerides were obtained and measured again after 1 month of treatment with the following two alternatives: 1) PC-300, one cup half an hour before eating, and 2) bezafibrate 200 mg/d.
- Detailed Description
It was a descriptive, prospective, longitudinal, and comparative clinical study developed at Ciprés Grupo Médico S.C. (CGM), Toluca, Mexico, from January 2014 to December 2014.
Patients with hypertriglyceridemia were invited to participate in the study. Voluntary subjects were assigned sequentially into two treatment groups: 1) fibrate (bezafibrate) 200 mg/day, and 2) PC-300 tea, one cup half an hour before eating.
Patients were measured (m) and weighed (kg) (Obi, México). Body mass index (BMI) was calculated as weight (kg) divided by height (m) squared. Blood pressure was measured with a calibrated sphygmomanometer (Welch Allyn, USA) after 5 min of rest.
All of the patients were given a low lipid diet. Calculated kcal were based on ideal weight minus 200 kcal/day if overweight.
Results were expressed as mean ± Standard deviation (SD). Differences between initial vs. final values were compared with the Mann-Whitney U test. The normality hypothesis was tested using the Kolmogorov-Smirnov test. A p value of \<0.05 was considered significant. All tests were performed with the SPSS ver. 23 statistical software program.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 34
- Patients with hypertriglyceridemia, aged >18 years and with an educational level at least of primary school.
- Patients with hepatic disease and those missing an appointment during the study.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description PC-300 tea PC-300 tea. Patients that received the Eryngium heterophyllum + Amphipterygium adstringens tea, one cup half an hour before eating. Bezafibrate Bezafibrate Patients that received fibrate (bezafibrate) 200 mg/day.
- Primary Outcome Measures
Name Time Method Triglycerides serum levels. One month. The triglycerides serum levels were measured at the recruiting moment and after one month..
- Secondary Outcome Measures
Name Time Method