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临床试验/CTRI/2024/08/072307
CTRI/2024/08/072307尚未招募不适用

Effect of Oral Vitamin D Supplementation on Post Orthodontic Relapse in Vitamin D Insufficient Individuals - A Quasi Experimental Study

Dr Anna Thomas P1 个研究点 分布在 1 个国家目标入组 35 人开始时间: 2024年9月2日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
35
试验地点
1
主要终点
Evaluation of post orthodontic relapse in Vitamin D insufficient patients post oral Vitamin D supplementation

研究概览

简要总结

The study aims to provide insights into whether vitamin D supplementation can help reduce post-orthodontic relapse in patients with vitamin D insufficiency, potentially offering a new approach to improve orthodontic treatment outcomes. The study targets patients in the settling phase of their orthodontic treatment and have been identified as having insufficient Vitamin D levels. The patients with deficient Vitamin D levels  will be given vitamin D supplements and then monitored for three months after their treatment is completed during the retention phase. Littles Irregularity Index will be used to measure the relapse. By comparing the tooth positions immediately after treatment and again three months later, we can determine if the vitamin D supplementation has any effect on reducing relapse - the tendency of teeth to move back towards their original positions after orthodontic treatment.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 30.00 Year(s)(—)
性别
All

入选标准

  • 1 Patients in settling phase of fixed orthodontic therapy.
  • 2 Patient with insufficient Vit D levels between 50-70 nmol/L(20-30 ng/ml) 3 Patients with deficient Vit D levels of less than 50nmol/L (less than 20 ng/ml) 4 Patients who provide oral and written consent to participation.

排除标准

  • Patients with history of midline diastema.
  • Patients with history of oral habits
  • Any craniofacial/developmental anomalies.
  • Congenitally missing/impacted teeth/ hypodontia excluding absent third molars.
  • Patients with debilitating diseases and bone metabolic disorders.
  • Patients on corticosteroids and anticonvulsants.
  • Patients already on Vitamin D supplements
  • Patients with very poor oral hygiene, with active periodontal diseases.

结局指标

主要结局

Evaluation of post orthodontic relapse in Vitamin D insufficient patients post oral Vitamin D supplementation

时间窗: Outcome will be assessed 3 months post orthodontic treatment

次要结局

  • Compliance and tolerability to Vit D supplement(2 months)

研究者

发起方
Dr Anna Thomas P
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Anna Thomas P

Indira Gandhi Institute of Dental Sciences, Pondicherry

研究点 (1)

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