A pilot assessor-blinded randomised controlled trial of Lee Silverman Voice Treatment versus standard NHS Speech and Language Therapy in Parkinson's Disease

Not Applicable

Completed

• Conditions: Parkinson's disease; Mental and Behavioural Disorders

• Registration Number: ISRCTN75223808
• Lead Sponsor: niversity of Birmingham (UK)

Brief Summary

2014 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/24908096 2018 results in: https://www.ncbi.nlm.nih.gov/pubmed/29344405

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-03-22
• Study Completion: 2013-10-31
• Last Update Posted: 19 February 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Idiopathic Parkinson?s disease defined by the UK PDS Brain Bank Criteria.
These criteria are in standard use throughout the NHS in the UK and were supported by the NICE guidelines.
2. PD patients who have self or carer-reported problems when asked:
Do you have any problems with your speech or voice? by their physician or PD nurse specialist
3. Male and female participants

Exclusion Criteria

1. Dementia as usually defined clinically by the patient?s physician. From our experience in PD MED, some patients with moderate to severe dementia have difficulty in completing self-assessment forms
2. Evidence of laryngeal pathology including vocal nodules or a history of vocal strain or previous laryngeal surgery within their medical records or from discussions with client, as LSVT is not appropriate for this group
3. Received SLT in the last 2 year
4. The investigator is certain the person will need SLT within 6 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
VHI - Voice Handicap Index measured at baseline, 3 months, 6 months & 12 months.

Secondary Outcome Measures

Name	Time	Method
1. AIDS - Assessment of Intelligibility of Dysarthic Speech measured at baseline, 3 months, 6 months<br>2. Comprehension Assessment measured at baseline, 3 months, 6 months<br>3. EQ-5D - Euroqol measured at baseline, 3 months, 6 months & 12 months<br>4. ICECAP-O measured at baseline, 3 months, 6 months & 12 months<br>5. LwD - Living with Dysarthia questionnaire measured at baseline, 3 months, 6 months & 12 months<br>7. Parkinson's Disease Carers' Questionnaire Quality of Life Assessment measured at baseline, 3 months, 6 months & 12 months<br>8. PDQ-39 - Parkinsons Disease Questionnaire 39 measured at baseline, 3 months, 6 months & 12 months<br>9. Resource Usage measured at 3 months, 6 months & 12 months<br>10. Vocal Loudness measured at baseline, 3 months, 6 months<br>11. V-RQoL - Voice related Quality of Life Scale measured at baseline, 3 months, 6 months & 12 months.