Misoprostol to treat Postpartum Haemorrhage (PPH): a randomised controlled trial (Argentina, Egypt, South Africa, Thailand and Viet Nam)

Completed

• Conditions: Postpartum haemorrhage; Pregnancy and Childbirth

• Registration Number: ISRCTN34455240
• Lead Sponsor: DP/UNFPA/WHO/World Bank - Special Programme of Research, Development and Research Training in Human Reproduction

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-06-07
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 1400

Inclusion Criteria

All women delivering vaginally with clinically diagnosed PPH thought to be due to or contributed to by atonia requiring additional uterotonics will receive either misoprostol or placebo in addition to routine treatment for PPH.

Exclusion Criteria

Refusal to give consent for participation; Too ill or distressed to give consent; The woman is not entitled to give informed consent e.g. minors without a guardian; The delivery is regarded as abortion according to the local gestational age limits; If the woman is delivered by caesarean section; If the woman cannot take misoprostol sub-lingually; If the woman suffers from severe bleeding disorder such as haemophilia; If the woman has a temperature of more than 38.5°C; If the woman has any severe allergic condition; If the woman's placenta is not delivered at the time of randomization.

Study & Design

• Study Type: Interventional
• Study Design: Not specified