Medical treatment of retained placenta: does it reduce the number of necessary surgical interventions? A randomised controlled trial in low resource setting

Completed

• Conditions: Retained placenta; Retained placenta and membranes; Pregnancy and Childbirth

• Registration Number: ISRCTN16104753
• Lead Sponsor: Tanzanian German Programme to Support Health (TGPSH) (Tanzania)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-04-21
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 117

Inclusion Criteria

Women with a retained placenta 30 minutes after delivery of the newborn (and a pregnancy duration of at least 28 weeks [birth weight 1 kg]). All women will receive active management of third stage of labour before inclusion.

Exclusion Criteria

1. Blood loss greater than 750 ml 30 minutes after delivery
2. Pulse rate greater than 120 beats/minute
3. Blood pressure (BP) dropped greater than 20 mmHg diastolic compared with BP before delivery
4. Anaemia (haemoglobin [Hb] less than 100 g/dl). Measurement of third trimester of pregnancy or around delivery

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in the amount of manual removal of placenta (under anaesthesia) 60 minutes after delivery of the baby.

Secondary Outcome Measures

Name	Time	Method
1. Blood loss<br>2. Need for blood transfusion<br><br>Hb will be checked the morning after the manual removal or the sponteneous expulsion of the placenta. After this it will be decided if a blood transfusion is necessary.