Misoprostol in the management of retained placenta - a safe alternative for manual removal? A randomised controlled trial

Not Applicable

Completed

• Conditions: Retained placenta; Pregnancy and Childbirth; Complications of labour and delivery

• Registration Number: ISRCTN45330307
• Lead Sponsor: eiden University Medical Centre (LUMC) (The Netherlands)

Brief Summary

2013 Results article in https://pubmed.ncbi.nlm.nih.gov/23231499/ (added 07/10/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-08-23
• Study Completion: 2009-08-01
• Last Update Posted: 18 October 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 99

Inclusion Criteria

1. All women with at least 25 completed pregnancy weeks and retained placenta
2. At least 18 years of age
3. Master the Dutch language in word and script

Exclusion Criteria

1. Excessive blood loss (greater than 1000 ml) within 60 minutes after the delivery of the newborn
2. Allergy for misoprostol or one of its components

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Number of spontaneous delivered placentas<br> 2. Number of manual removals and amount of blood loss<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. Interval between delivery of the baby and administration of misoprostol<br> 2. Interval between administration of misoprostol and delivery of the placenta<br> 3. Placenta captiva<br>