Cerebrospinal Fluid Collection and Repository Storage
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Nervous System Diseases
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- Enrollment
- 51
- Locations
- 1
- Primary Endpoint
- The primary objective of this study is to create a repository of CSF and matched serum and plasma samples.
- Status
- Terminated
- Last Updated
- last year
Overview
Brief Summary
Background:
- Cerebrospinal fluid (CSF) is the liquid around the brain and spinal cord. Many diseases can only be diagnosed by examining the CSF. A lumbar puncture is used to collect and test CSF. Once someone is already having a lumbar puncture, a small extra amount of CSF can be collected at the same time. This fluid can be used to study brain, nerve, and related health issues. Researchers want to collect CSF and blood samples from people who are scheduled to have a lumbar puncture.
Objectives:
- To collect cerebrospinal fluid and blood samples from individuals who are having a lumbar puncture.
Eligibility:
- Individuals between 2 and 100 years of age who are scheduled to have a lumbar puncture for clinical or research purposes.
Design:
- Participants will have a lumbar puncture for clinical or research purposes.
- During the procedure, an additional sample of CSF will be collected. They will also provide a blood sample, if one is not taken at the time of the procedure.
- Treatment will not be provided as part of this study.
Detailed Description
In this study we are planning to establish a repository of cerebrospinal fluid (CSF), serum, and plasma. We are planning to collect a small amount of additional CSF and blood on subjects who are already going to have a lumbar puncture as part of their research or clinical care at the National Institutes of Health (NIH). This will allow us to study whether there is an association between neurological diseases and biomarkers, help identify novel pathogens infecting the central nervous system, and better enable us to understand the immune response to infections under future protocols. CSF and blood as well as clinical data associated with the samples will be stored securely.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
The primary objective of this study is to create a repository of CSF and matched serum and plasma samples.
Time Frame: ongoing
Repository of CSF and matched blood.