PACTR202306656398595
Not yet recruiting
Phase 3
Chest ultrasonographic evaluation after intrapleural Alteplase versus Streptokinase injection in Children with Empyema
Assiut University Children Hospital.0 sites75 target enrollmentMarch 7, 2023
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Respiratory
- Sponsor
- Assiut University Children Hospital.
- Enrollment
- 75
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age: from1 month to18 years.
- •Gender: both sexes will be included in the study.
- •Empyema or CPPE along with evidence of septated pleural effusion on chest ultrasonography.
- •All patients will undergo chest tube insertion along with intravenous antibiotics.
Exclusion Criteria
- •Age below 1 month.
- •Patients with chronic empyema which is characterized by thickened visceral and parietal peels which hamper the ability of affected lung to re\-expand and required definitive surgical intervention.
- •Patients with bleeding tendency, recent trauma, recent operation and on anticoagulation.
- •Children with pleural empyema from tuberculosis or malignancy.
- •Children with allergy to tPA or streptokinase.
- •Children with minimal parapneumonic effusion that do not require chest tube insertion.
- •Presence of bronchopleural fistula or pyopneumothorax.
Outcomes
Primary Outcomes
Not specified
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