Chest ultrasonographic evaluation after intrapleural Alteplase versus Streptokinase injection in Children with Empyema

Assiut University Children Hospital.0 个研究点目标入组 75 人开始时间: 2023年3月7日最近更新: 2024年3月4日

适应症

试验速览

暂无简介。

•Age: from1 month to18 years.
•Gender: both sexes will be included in the study.
•Empyema or CPPE along with evidence of septated pleural effusion on chest ultrasonography.
•All patients will undergo chest tube insertion along with intravenous antibiotics.

•Age below 1 month.
•Patients with chronic empyema which is characterized by thickened visceral and parietal peels which hamper the ability of affected lung to re-expand and required definitive surgical intervention.
•Patients with bleeding tendency, recent trauma, recent operation and on anticoagulation.
•Children with pleural empyema from tuberculosis or malignancy.
•Children with allergy to tPA or streptokinase.
•Children with minimal parapneumonic effusion that do not require chest tube insertion.
•Presence of bronchopleural fistula or pyopneumothorax.

发起方

Assiut University Children Hospital.