the Evaluation of Green Coffee Extract Supplementation on Adropin, Irisin, Vaspine,Systemic Inflammation and Oxidative Stress in Breast Cancer Survivors
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Interleukin 6
研究概览
简要总结
To study the effects of green coffee supplement on adropin, irisin, vaspine, systemic inflammation and oxidative stress in breast cancer survivors.50 breast cancer survivors who their treatment is over and referred to follow breast cancer clinic with will be randomly allocated to receive placebos or 2 capsules green coffe for 12 weeks; both groups will be advised to adherence the investigators' diet and exercise program too. At the first and the end of the intervention, adropin, irisin, vaspine, systemic inflammation and oxidative stress will be assessed and compared between groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age of 18 to 70 years
- •Body Mass Index (BMI) between 25-40 treatment is over
排除标准
- •Taking any kind of supplement for weight reduction
- •pregnancy or lactation
- •Professional athletes
研究组 & 干预措施
green coffe
2 capsuls of green coffe
干预措施: green coffee (Dietary Supplement)
control
2 capsuls
干预措施: control (Other)
结局指标
主要结局
Interleukin 6
时间窗: 12 weeks
assessed by ELISA
Tumor necrosis factor alpha
时间窗: 12 weeks
assessed by ELISA
次要结局
- body mass index(12 weeks)
研究者
Dr Azita Hekmatdoost
Principal Investigator
National Nutrition and Food Technology Institute