Pathophysiologic Changes in the Respiratory System During Therapeutic Interventions

Completed

• Conditions: Respiratory Failure

• Registration Number: NCT01239433
• Lead Sponsor: Oslo University Hospital

Brief Summary

Airway pressures change during fiberoptic bronchoscopy and endotracheal suctioning. In this study pressure changes are examined in a mechanical lung model and in a population of ICU patients on mechanical ventilation.

Detailed Description

Airway pressures change during fiberoptic bronchoscopy and endotracheal suctioning. In this study such pressure changes are examined in a mechanical lung model and in a population of ICU patients on mechanical ventilation. A systematic recording of airway pressures, tidal volumes and blood gases are carried out during ordinary therapeutic procedures requested by the staff physician. No additional study interventions are carried out.

The aim of the project is to examine negative effects of pressure/volume changes.

Study Timeline

• Study First Submitted: 2010-11-10
• Study First Submitted QC: 2010-11-10
• Study First Posted: 2010-11-11
• Study Start: 2011-05
• Primary Completion: 2016-05
• Study Completion: 2016-05
• Status Verified: 2016-09
• Last Update Submitted: 2016-09-26
• Last Update Posted: 2016-09-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• > 18 years of age
• on mechanical ventilation
• daily endotracheal suctioning performed

Exclusion Criteria

• < 18 years of age
• non-invasive ventilation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intrabronchial airway pressure	2013

Trial Locations

Locations (1)

Oslo University Hospital - Ulleval; 🇳🇴 Oslo, Norway