Exploratory Study of the Interest of MRI Susceptibility Weighted Imaging for the Pre-operative Assessment of Pelvic Endometriosis Extent
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 74
- 试验地点
- 2
- 主要终点
- Interest of MRI Susceptibility Weighted Imaging
研究概览
简要总结
Knowledge of the precise location of endometriosis is essential for a successful surgical treatment. MRI Susceptibility-Weighted Imaging (SWI-MRI) yields high sensitivity for blood by-products detection. Since endometriosis lesions are haemorrhagic, and therefore rich in blood by-products such as hemosiderin, SWI-MRI could be useful in the pre-operative assessment of endometriosis, especially in superficial peritoneal lesion detection. The purpose of our study is to evaluate the performance of SWI-MRI for the preoperative work-up of endometriosis
详细描述
Pelvic endometriosis is a cause of pelvic pain, dysmenorrhea, urinary symptoms and infertility. MRI is considered as the best imaging technique to detect and to predict the extent of the disease. Susceptibility Weighted Imaging is routinely performed to identify haemorrhagic lesions in brain MRI protocols and has proven to be a sensitive technique to detect blood by-products. A pelvic MRI protocol including SWI will be performed in all women addressed for diagnostic assessment or pre-operative work-up of endometriosis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Adult woman (over 18yrs old) addressed for diagnostic assessment or pre-operative work-up of endometriosis;
- •Informed signed consent
- •Affiliated or beneficiary of a social security system
排除标准
- •Patient <18yrs old
- •Pregnant or nursing woman
- •Patient under legal protection
- •Contraindication to MRI
研究组 & 干预措施
SWAN sequence
Susceptibility Weighted Imaging as 3D SWAN sequence
干预措施: Susceptibility Weighted Imaging as 3D SWAN sequence (Other)
结局指标
主要结局
Interest of MRI Susceptibility Weighted Imaging
时间窗: Baseline (MRI) and day of surgery
The diagnostic use of SWI-MRI will be assessed through: * the number of endometriotic locations, which are both identified with SWI-MRI and confirmed by surgery. * the sensitivity, specificity, and predictive values of MRI. * signal intensities of each endometriotic location found in surgery on T1 weighted sequence (presence of a high signal intensity) and SWI (presence of a low signal intensity)
次要结局
- Deep forms of endometriosis(Baseline (MRI) and day of surgery)
- Superficial forms of endometriosis(Baseline (MRI) and day of surgery)