NCT00156598终止不适用
Cobalt, Chromium and Titanium Serum Concentrations in Patients With Metal-on-Metal vs. Metal on Polyethylene Total Hip Replacements
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 5
研究概览
简要总结
Other research studies have shown that the levels of metals in the blood are slightly increased after patients receive a total hip replacement. We want to learn whether these elevated levels are associated with any adverse effects. We hope this study will help us identify which type of patients have elevated levels of metal in their blood.
详细描述
It is suspected that the concentration of the metals chromium, cobalt and titanium in the blood will be higher in people with an all metal total hip prosthesis than in those with a plastic and metal prosthesis. To find out if this is true, we will test blood samples for the levels of metal in the blood and compare the values from 3 groups of people:
- people with metal on metal hip replacements
- loosening of a plastic and metal prosthesis and
- evidence of osteoarthritis and are awaiting a total hip replacement.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Group 1 - unilateral hip replacement with metal on metal prosthesis, well functioning.
- •Group 2 - loosening of plastic and metal prosthesis Group 3 - osteoarthritis of the hip and awaiting total hip replacement
排除标准
- •renal dysfunction
- •other types of metal implants or dental prostheses
- •rheumatoid arthritis
- •hip infection
研究者
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