Effect of Tamsulosin vs Prazosin in Treatment of Female Voiding Dysfunction
- Registration Number
- NCT00602186
- Lead Sponsor
- Tabriz University
- Brief Summary
The purpose of this study is to determine whether Tamsolusin or Prazosin are effective in the treatment of female voiding dysfunction(BOO)
- Detailed Description
Voiding dysfunction is not uncommon in Tabriz.About 20% of patients in female urology clinic of Tabriz university of medical sciences sufered from some degrees of voiding dysfunction (due to bladder imparement or bladder outlet obstruction).There is limited information about medical treatment of those patients. On the other hand alpha adrenergic blockers are the first choice medication in BENIGN PROSTATIC HYPERPLASIA. There is some new facts about destribution of alpha adrenergic blockers in female pelvic floor.The purpose of this study is to comparision whether Tamsolusin 0.4/daily or Prazosin 1 mg/daily are effective in the treatment of female voiding dysfunction(BOO)
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 80
- Healthy females with voiding difficulty with MFR<12 and post void residual urine>50cc
- History of pelvic floor surgury during last 3 month
- Any contraindication for Tamsolusin or prazosin
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 tamsolusin taking Tamsulosin 2 prazosin taking prasosin
- Primary Outcome Measures
Name Time Method patient symptoms improvement(Standard questionare) every month untile 3 months
- Secondary Outcome Measures
Name Time Method Urodynamics parameters improvement three months later