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Clinical Trials/NCT01128660
NCT01128660
Completed
Not Applicable

Assessment of the Prescriber's and the Pharmacies Overview of Patient Medication by Use of the Fidelity Coefficient.

University of Southern Denmark1 site in 1 country283,388 target enrollmentJune 2010

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Misuse of Prescription Only Drugs
Sponsor
University of Southern Denmark
Enrollment
283388
Locations
1
Primary Endpoint
FC(Pharm)
Status
Completed
Last Updated
13 years ago

Overview

Brief Summary

The purpose of this study is to twofold. The investigators wish to introduce a new patient-descriptive parameter, the 'Fidelity Coefficient', and use it to assess and compare the overview of patient's medication possessed by the general practitioners and the pharmacies.

Detailed Description

The fidelity coefficient, FC, is a measure of what proportion of individual patients' medication that are accounted for by the most used prescriber and the most used pharmacy. Each patient therefore has two values, one describing his fidelity towards his most used prescriber, FCPresc, and one describing his fidelity towards his most used pharmacy, FCPharm. The investigators intend to assess this parameter in an observational population scale database study, using standard descriptive statistics, and subsequently compare the obtained average FCPresc and FCPharm. Furthermore, the investigators will analyze the two obtained FCs for dependency of a predefined list of variables: age, gender, number of prescriptions, whether the most frequent prescriber was a GP and whether the most used pharmacy was urban. Finally, the investigators intend to analyze which medications (grouped using the ATC-system with 4 digits, e.g. C07A) that has the highest proportion of prescriptions that were either issued by a non-main prescriber or redeemed at a non-main pharmacy, which roughly translates into the most 'infidel' medications. To insure relevance we intend to use a cut-off-value of the medication being prescribed at least 50.000 times, which equals about 85 % of the data according to preceding analyses. The data for this study will be obtained from the Odense University Pharmacoepidemiological Database (OPED). In brief, it is a research database with full coverage of all reimbursed prescriptions in the Region of Southern Denmark (1.2 million inhabitants). The data included in each prescription record includes the prescription holder, the prescriber, the pharmacy, the date of dispensing and a full account of the dispensed product, including substance, brand name, route of administration, ATC-code and Defined Daily Dose (DDD). Some drugs are exempt from re-imbursement and thus not covered by the database, including benzodiazepines, oral contraceptives, laxatives and certain antibiotics.

Registry
clinicaltrials.gov
Start Date
June 2010
End Date
August 2010
Last Updated
13 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jesper Hallas

Professor of Clinical Pharmacology

University of Southern Denmark

Eligibility Criteria

Inclusion Criteria

  • Having filed more than 9 prescriptions during 2009.

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

FC(Pharm)

Time Frame: cross-sectional study with data aquisition over one year

The pharmacy fidelity coefficient, FC(Pharm), is a measure of what proportion of individual patients' medication that are accounted for by the most used pharmacy.

Study Sites (1)

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