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临床试验/NCT04800900
NCT04800900已完成不适用

Effectiveness of Pharmaceutical Interventions in the Omission of Prescription and Desprescription of Medications in Hospitalized Patients

Federal University of Bahia2 个研究点 分布在 1 个国家目标入组 332 人开始时间: 2021年2月4日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
332
试验地点
2
主要终点
Effectiveness of pharmaceutical interventions measured by proportion of accepted interventions and all interventions

研究概览

简要总结

The presence of multimorbidities is very common among the elderly, which become major consumers of medicines. The process of prescribing medicines for the elderly should be done with caution, as the use of some medications may present more risks than benefits in this range age. Potentially inappropriate prescribing for the elderly has become a global concern for the promotion of an adequate pharmacotherapy, it becomes essential to be aware of the effectiveness and safety of medicines and the knowledge of which drugs whose risks of serious adverse reactions outweigh the benefit of your referral. In this sense, the present study has aim to evaluate the effectiveness of pharmaceutical interventions in frequency of omission of drugs with proven efficacy for cardiovascular diseases and promotion of treatment prescription inappropriate and polypharmacy. A prospective quasi experimental before and after study will be carried out in elderly patients diagnosed with cardiovascular disease admitted to the Ana Nery hospital, Salvador, Bahia, Brazil. A convenience sample will be collected, the data will be released and revised in a database built in the SPSS software and analyzed in the program statistic R and SPSS. At the end of the study, it is expected a decrease in the frequency of omission of medications and promotion of prescription drugs inappropriate.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Other
盲法
None

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Clinical diagnosis of cardiovascular disease
  • Discharge after 24 hours

排除标准

  • 未提供

结局指标

主要结局

Effectiveness of pharmaceutical interventions measured by proportion of accepted interventions and all interventions

时间窗: The acceptance of all pharmaceutical interventions related to inappropriate prescribed drugs and omission of prescription during the hospitalization of the patient will be evaluated, through study completion, an average of 1 year

次要结局

  • Incidence of omission of prescription drugs with proven efficacy for cardiovascular diseases measured by the START criteria(First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year)
  • Incidence of polypharmacy in elderly people with cardiovascular diseases measured by prescription containing five or more drugs(First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year)
  • Incidence of potentially inappropriate drug prescription in elderly people with cardiovascular diseases measured by the Beers criteria(First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year)

研究者

发起方
Federal University of Bahia
申办方类型
Other
责任方
Principal Investigator
主要研究者

Márcio Galvão Guimarães de Oliveira

Clinical Professor of Pharmacy and Evidence-based Health Care

Federal University of Bahia

研究点 (2)

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