Perioperative regional cerebral and peripheral oxygen saturation, EEG and hemodynamics in surgical neonates - an observational pilot study

• Conditions: onderzoek na hersenfunctie peroperatief bij pasgeboren kinderen; Cerebral function - brain function

• Registration Number: NL-OMON45238
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

* Postnatal age * 4 weeks
* Surgery under general anaesthesia
* Written informed parental consent

Exclusion Criteria

* Contraindications for the use of inhalation anaesthetics
* Preoperative invasive ventilatory support
* Anticipated difficult airway
* Thoracoscopic- or cardiac surgery
* surgical procedures resulting in limited acces to the head for the anaesthetist (i.e. ENT- surgery)
* No written informed parental consent

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Impact of general anaesthesia on cerebral (and peripheral tissue) regional<br /><br>oxygen saturation, recorded as quantified variables. Comparison of those<br /><br>variables under anaesthetised conditions with data recorded before and after<br /><br>the surgical procedure (non-anaesthetised conditions). Analysis of the EEG in<br /><br>order to describe potential typical patterns under anaesthetised conditions,<br /><br>focusing on density spectral array and amplitude integrated EEG.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-</p><br>