Outcome of furosemide and oral sodium chloride as alternative treatment for syndrome of inappropriate antidiuresis with fluid restriction failure.

Recruiting

• Conditions: Hyponatremia from SIADH Failure to fluid restriction treatment; SIADH, Fluid restriction, Furosemide, Oral sodium chloride

• Registration Number: TCTR20221205002
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-12-05
• Last Update Posted: 19 August 2024
• Study Completion: 2025-09-30

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

1. Hyponatremic patients diagnosed with SIADH by Barrter and Schwartz criteria
2. Failure to respond to fluid restriction treatment
3. Age more than 15 years old
4. Asymptomatic hyponatremia

Exclusion Criteria

1. Chronic diuretic therapy
2. Hemodynamic instability
3. Severe hyperglycemia define as blood sugar > 300 mg/dL
4. can not take food by oral or enteral feeding
5. Deny participating in this clinical trial

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Treatment failure rate at 7 days after treatment percent

Secondary Outcome Measures

Name	Time	Method
Sensitivity and specificity of urine sodium at 7 days after treatment percent,Sensitivity and specificity of urine serum electrolyte ratio at 7 days after treatment percent,Sensitivity and specificity of urine osmole at 7 days after treatment percent,Sensitivity and specificity of serum urea at 7 days after treatment percent