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Clinical Trials/NCT02059200
NCT02059200
Completed
N/A

The Effectiveness of Mindfulness Based Compassionate Living in Recurrent Depression

Radboud University Medical Center1 site in 1 country122 target enrollmentJuly 2013

Overview

Phase
N/A
Intervention
Not specified
Conditions
Recurrent Depression
Sponsor
Radboud University Medical Center
Enrollment
122
Locations
1
Primary Endpoint
Beck Depression Inventory-II
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Since a few years, Mindfulness Based Cognitive Therapy (MBCT) has been used as treatment for patients suffering from recurrent depression. Though a number of studies show that MBCT is effective in this population and MBCT reduces the chances of relapse/recurrence in recurrent depressive patients, the chance of a new depression developing after end of treatment is still considerable. Ergo, there is room for improvement.

Especially the development of a non-judging or compassionate attitude towards all experience seems to mediate the treatment effect. It is therefore our expectation that a follow-up intervention that focuses specifically on self-compassion could prove very useful in elaborating on the effects of MBCT.

The research question of this research is therefore: what is the effect of compassion training in people suffering from recurrent depression who have already received MBCT training?

Registry
clinicaltrials.gov
Start Date
July 2013
End Date
November 2015
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Anne Speckens

Professor

Radboud University Medical Center

Eligibility Criteria

Inclusion Criteria

  • Recurrent depression according to the DSM-IV criteria.
  • Having participated in an MBCT training (\>= 4 sessions)

Exclusion Criteria

  • One or more previous (hypo)manic episodes according to DSM-IV criteria.
  • Primary psychotic disorder, e.g. schizophrenia or delusions.
  • Clinically relevant neurological conditions (e.g. brain trauma or dementia) or somatic conditions (e.g. cancer, AIDS) that could be related to the depression.
  • Current alcohol and/or drug abuse.
  • Use of high dosages of benzodiazepines.
  • Recent electro convulsive therapy (ECT) (less than 3 months ago).
  • Problems impeding participating in a group, such as severe borderline personality disorder.
  • No prior experience with MBCT.
  • Problems impeding completing the questionnaires, such as cognitive dysfunctions (only assessed if suspected).
  • Subnormal intelligence (IQ \< 80) (only assessed if suspected).

Outcomes

Primary Outcomes

Beck Depression Inventory-II

Time Frame: 1 year

The BDI-II measures depression symptoms. Measurements will be taken at baseline, end of treatment/control and follow up.

Secondary Outcomes

  • Five Facet Mindfulness Questionnaire(1 year)
  • The Acceptance and Action Questionnaire-II(1 year)
  • Self-Compassion Scale(1 year)
  • Fears of Compassion Scale (3)(1 year)
  • The Ruminative Response Scale(1 year)
  • The Childhood Trauma Questionnaire(Baseline)
  • Types of Positive Affect Scale(1 year)
  • The World Health Organization Quality of Life Scale(1 year)

Study Sites (1)

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