Mindfulness-based Cognitive Therapy for Chronic Depression
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 106
- 试验地点
- 2
- 主要终点
- Hamilton Rating Scale for Depression
研究概览
简要总结
The propose of the study is to investigate the efficacy of Mindfulness-based Cognitive Therapy (MBCT, Segal, Williams, & Teasdale, 2002) for patients suffering from Chronic Major Depression. The efficacy of MBCT will be compared with the Cognitive Behavioral Analysis System of Psychotherapy (McCullough, 2003), a treatment approach, which has proven it's efficacy yet, and with a treatment-as-usual condition (standard psychiatric outpatient care).
详细描述
Cognitive Behavioral Analysis System of Psychotherapy (CBASP) is a treatment approach specifically developed for the treatment of chronic depression. CBASP aims to change dysfunctional interpersonal patterns. Mindfulness-based Cognitive Therapy (MBCT) has recently been proposed as a further treatment option for chronic depression. MBCT trains patients to step out of negative ruminative states of mind. There are no direct comparisons of the psychological treatment options for chronic depression.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnoses of Major Depression, single episode, chronic or
- •Major Depression, recurrent, chronic
- •Hamilton Rating Scale for Depression score > 14
- •Beck Depression Inventory II score > 14
排除标准
- •History of Schizophrenia or Schizoaffective Disorder
- •Current Substance Dependence or Eating Disorder
- •Mental Disorder Due to General Medical Condition
- •Borderline Personality Disorder
结局指标
主要结局
Hamilton Rating Scale for Depression
时间窗: Change from Baseline in HAM-D at 8 weeks
次要结局
- Beck Depression Inventory II(Change from Baseline in BDI-II at 6 months)
- Social Adaption Self-evaluation Scale(Change from Baseline in SASS at 6 months)
- Short Form (36) Health Survey(Change from Baseline in SF-36 at 6 months)
- Global Assessment of Functioning Scale(Change from Baseline in GAF at 6 months)
- Response Styles Questionnaire(Change from Baseline in RSQ at 6 months)
研究者
Johannes Michalak
Prof. Dr. phil.
Ruhr University of Bochum