Mindfulness-based Cognitive Therapy for Chronic Depression
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Chronic Major Depression
- Sponsor
- Johannes Michalak
- Enrollment
- 106
- Locations
- 1
- Primary Endpoint
- Hamilton Rating Scale for Depression
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
The propose of the study is to investigate the efficacy of Mindfulness-based Cognitive Therapy (MBCT, Segal, Williams, & Teasdale, 2002) for patients suffering from Chronic Major Depression. The efficacy of MBCT will be compared with the Cognitive Behavioral Analysis System of Psychotherapy (McCullough, 2003), a treatment approach, which has proven it's efficacy yet, and with a treatment-as-usual condition (standard psychiatric outpatient care).
Detailed Description
Cognitive Behavioral Analysis System of Psychotherapy (CBASP) is a treatment approach specifically developed for the treatment of chronic depression. CBASP aims to change dysfunctional interpersonal patterns. Mindfulness-based Cognitive Therapy (MBCT) has recently been proposed as a further treatment option for chronic depression. MBCT trains patients to step out of negative ruminative states of mind. There are no direct comparisons of the psychological treatment options for chronic depression.
Investigators
Johannes Michalak
Prof. Dr. phil.
Ruhr University of Bochum
Eligibility Criteria
Inclusion Criteria
- •Clinical diagnoses of Major Depression, single episode, chronic or
- •Major Depression, recurrent, chronic
- •Hamilton Rating Scale for Depression score \> 14
- •Beck Depression Inventory II score \> 14
Exclusion Criteria
- •History of Schizophrenia or Schizoaffective Disorder
- •Current Substance Dependence or Eating Disorder
- •Mental Disorder Due to General Medical Condition
- •Borderline Personality Disorder
Outcomes
Primary Outcomes
Hamilton Rating Scale for Depression
Time Frame: Change from Baseline in HAM-D at 8 weeks
Secondary Outcomes
- Beck Depression Inventory II(Change from Baseline in BDI-II at 6 months)
- Social Adaption Self-evaluation Scale(Change from Baseline in SASS at 6 months)
- Short Form (36) Health Survey(Change from Baseline in SF-36 at 6 months)
- Global Assessment of Functioning Scale(Change from Baseline in GAF at 6 months)
- Response Styles Questionnaire(Change from Baseline in RSQ at 6 months)