Clinical Research on the Efficacy and Feasibility of Laparoscopic Complete Mesocolic Excision on Colon Cancer: A Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 99
- 试验地点
- 1
- 主要终点
- Histopathological Outcomes Obtained Through the Surgeries
研究概览
简要总结
Laparoscopic complete mesocolic excision is a concept that using laparoscopic surgery technique to perform a resection for colon cancer. Besides, the segment of the colon containing the tumor, the resection area should include an intact mesocolon as an envelope to encase the possible route for metastasis. The routes include blood vessels, lymphatic drain and etc. Such hypothesis predicts better histopathological and higher oncological results which turns into better survival rate and better quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 79 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with pathologically confirmed colon cancer
- •Signed consent
排除标准
- •History of malignancy
- •Intestinal obstruction or perforation
- •Evidence of metastasis by preoperative examinations
- •Deformity of spine
- •Emergency case
- •BMI > 29
研究组 & 干预措施
laparoscopic complete mesocolic excision
Randomized group of patients receiving laparoscopic colectomy with the concept of complete mesocolic excision
干预措施: laparoscopic complete mesocolic excision (Procedure)
D3 laparoscopic colectomy
Randomized group of patients receiving laparoscopic colectomy with D3-resection
干预措施: D3-laparoscopic colectomy (Procedure)
结局指标
主要结局
Histopathological Outcomes Obtained Through the Surgeries
时间窗: 14 days after the surgery
number of lymph nodes retrieved
次要结局
- Survival Rate(3 years after the surgery)
研究者
Bo Feng
Research chair of MIS
Ruijin Hospital