Effects of Autologus Platelet- Rich Plasma on ICSI outcomes and Pregnancy Rate in frozen embryo transfer cycles in Repeated Implantation Failure Patients
Not Applicable
Recruiting
- Conditions
- Infertility, recurrent implantation failure.Complication associated with artificial fertilization, unspecified
- Registration Number
- IRCT2017073034422N2
- Lead Sponsor
- Avicenna Research Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
patient who has at least 2 cycle IVF failure; At least 6 good quality embryos were transferred in previous cycles; Semen count=10 millions,normal morphology =3% in semen analysis
Exclusion criteria:
1-patient without immunologic disorders (abnormality in CD markers, Anti TG, Anti TPO, ds DNA, ANA); hematologic disorder; genetic diseases; uterus disorders; Hb<11 mg/dl and Platelet<150000/mm3; use of corticosteroid during 14 days before of PRP
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Chemical pregnancy rate. Timepoint: Two weeks after intervention. Method of measurement: Beta HCG in blood.
- Secondary Outcome Measures
Name Time Method Implantation Rate. Timepoint: Six weeks after intervention. Method of measurement: Calculation (number of embryos transfer /number of pregnancy sacs in sonography 6 weeks after ET).