A comparison of Ondansetron vs. Metoclopramide for treatment of nausea and vomiting in pregnancy
Phase 2
- Conditions
- Severe nausea and vomiting of pregnancy.Excessive vomiting in pregnancy
- Registration Number
- IRCT138902161760N6
- Lead Sponsor
- Vice Chancellor for Research and Technology, Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
pregnant women with gestational age less than 16 weeks based on the last menstrual period and ultrasound, with symptoms of vomiting for more than three times a day, or weight loss more than three kilograms or positive urine ketones. Exclusion criteria: presence of internal diseases at the same time, and hydatidiform mole and twin pregnancy.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of clinical symptoms. Timepoint: Before and after treatment. Method of measurement: Based on VAS.
- Secondary Outcome Measures
Name Time Method Recurrence rate of nausea and vomiting. Timepoint: One week after discontinuation. Method of measurement: Based on VAS.