Comparison of Effectiveness of Ondansetron versus Metoclopramide in Hyperemesis Gravidarum

Phase 3

• Conditions: hyperemesis gravidarum.; Hyperemesis gravidarum with metabolic disturbance; O21.1

• Registration Number: IRCT20190528043735N1
• Lead Sponsor: Zanjan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 November 2019

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 154

Inclusion Criteria

clinical signs of nausea , vomiting and dehydration
gestational age <16 weeks from the first day of the last menstruation
ketonuria
oral intolerance

Exclusion Criteria

gastrointestinal disorders justify nausea and vomiting
multiple pregnancy
having certain diseases, such as diabetes, asthma and urinary tract infection
taking any medicine other than folic acid

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ausea and vomiting. Timepoint: beginning of study and 24 ,48 hours after starting treatment. Method of measurement: questionnaire PUQE (Pregnancy Unique Quantification of Emesis).

Secondary Outcome Measures

Name	Time	Method
Duration of intravenous fluid intake. Timepoint: from start to end of treatment. Method of measurement: review patient medical records and calculate the hours of intake of fluids.;Number of intravenous doses received. Timepoint: from start to end of treatment. Method of measurement: review patient medical records and calculate the number of doses of medication received.;Length of hospitalization. Timepoint: from start to end of treatment. Method of measurement: review patient medical records and calculate the number of hospita admissions days.