NCT00517322Unknown4 期
Left Atrial Remodelling in Hypertension: Effects of Ramipril or Irbesartan
Università degli Studi dell'Insubria1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2007年8月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- diastolic function
研究概览
简要总结
Aim of the study is to compare in hypertensive patients the effect of one year therapy with ACE-inhibitor (RAMIPRIL) or angiotensin II receptor blocker (IRBESARTAN) on left atrial remodelling and diastolic function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 40 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •mild to moderate essential hypertension
- •no antihypertensive treatment
- •good quality echocardiogram
排除标准
- •cardiovascular diseases (AMI, stroke o TIA)
- •heart failure, valvular heart disease
- •secondary hypertension
- •atrial fibrillation
- •hepatic and renal severe failure
- •pregnancy
研究组 & 干预措施
1
Experimental
treatment with ramipril
干预措施: ramipril (Drug)
2
Experimental
treatment with irbesartan
干预措施: irbesartan (Drug)
结局指标
主要结局
diastolic function
时间窗: one year
left atrial volume
时间窗: one year
次要结局
- systolic and diastolic blood pressure(one year)
研究者
研究点 (1)
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