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A case control study on the effects of incomplete, one, and more than one dexamethasone course on acute respiratory problems in twins preterm neonates born between 280-366 weeks of gestatio

Completed
Conditions
The abnormal breathing problems of premature babies
steroid, dose, abnormal breathing problem, twins, premature baby
Registration Number
TCTR20221123002
Lead Sponsor
Faculty of Medicine, Siriraj Hospital
Brief Summary

A complete antenatal corticosteroid course in twin preterm pregnancies is associated with reduced adverse respiratory outcomes, underscoring the need for the judicious use of both incomplete and multiple steroid courses.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Female
Target Recruitment
1800
Inclusion Criteria

1. Twins babies born prematurely during 28 weeks -36weeks 6 daysof gestation
2. Mothers have a history of dexamethasone administration before preterm delivery

Exclusion Criteria

Premature infants whose mothers had not received prenatal steroid injections.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Respiratory problem 2 hours after delivery respiratory rate/ beats per minutes
Secondary Outcome Measures
NameTimeMethod
respiratory distress in premature infants, early, moderate and late preterm 2 hours after delivery respiratory rate/ beats per minute
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