Exploratory measurement of the physiological effects, induced through changes in afterload, of left ventricular strain-volume loop
- Conditions
- one, we will test healthy control subjects
- Registration Number
- NL-OMON28914
- Lead Sponsor
- Radboud University Medical Center Nijmegen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Age between 18 and 30 or above 60
- Male gender
Exclusion Criteria
- History of cardiovascular diseases
- Diabetes Mellitus
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary study parameter will be the slope of the systolic strain-volume relation (Sslope)
- Secondary Outcome Measures
Name Time Method The secondary parameters will be the early systolic strain (ԑ_ES), peak strain (peak ԑ) and the dissociation between the systolic and diastolic strain-volume relation during early diastole (UNCOUP_ED) and late diastole (UNCOUP_LD).