Post-COVID-19 Chronic Fatigue Syndrome
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 528
- 试验地点
- 1
- 主要终点
- Fatigue scale
研究概览
简要总结
Fatigue is recognized as one of the most commonly presented long-term complaints in individuals previously infected with SARS-CoV-2.
详细描述
It has become increasingly clear that infected patients have symptoms not only in the acute phase, but also after recovery from the initial infection.
A recent meta-analysis including 4828 patients with post-COVID-19 showed that symptoms and post-acute sequelae of SARS-CoV-2 can persist weeks to months after the infection.
These patients who reported persistent symptoms have been termed "long haulers" or described as having long COVID, post-acute COVID-19, persistent COVID-19 symptoms, post COVID-19 manifestations, long-term COVID-19 effects, post-acute sequelae of COVID-19 (PASC), or post-COVID-19 syndrome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or female
- •Post-Covid-19 Fatigue
排除标准
- 未提供
研究组 & 干预措施
Synthetic Vitamin B1
Synthetic Vitamin B1, 400 mg per day
干预措施: Synthetic Vitamin B1 (Drug)
结局指标
主要结局
Fatigue scale
时间窗: three month
chalder fatigue scale: the minimum = 0 and maximum values = 33, and whether higher scores mean a worse outcome.
次要结局
- Incidence of adverse events(6 months)
研究者
Emad R Issak
Dr
ClinAmygate