Preoperative training and nutrition in the 'Active Recovery' care pathway

Conditions: patients with osteoarthritis and sarcopenic obesity

Registration Number: NL-OMON28555

Lead Sponsor: /A

Brief Summary: /A

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 34

Inclusion Criteria

•scheduled for THA or TKA with a waiting period of minimal 6 weeks (which is the usual waiting period)
•OA as reason for THA or TKA
•Having obesity (BMI =30 kg/m2)
•Having muscle weakness (Men: Hand Grip Strength (HGS) <27kg; Women: HGS <16kg or Chair stand >15sec for five rises) 12
•Adequate cognitive functioning (the patient is capable to understand instructions and to per-form the screening)
•Age 18 years or older

Exclusion Criteria

•Unable to understand Dutch
•Patients diagnosed with dementia
•Patients who are unable to exercise due to comorbidities/ contra-indications. Absolute con-tra-indications for exercise are listed in the Dutch guideline for OA 13 and in the ACSM's Guidelines for Exercise Testing and Prescription 14. See appendix 1 for additional information about contraindications and considerations when prescribing exercises to older people with comorbidity.
•Patients with severe renal insufficiency or an eGFR<30 (estimated Glomerular Filtration Rate)

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Feasibility is assessed by adherence to the treatment, inclusion and dropout rate, adverse events and the patient appreciation and motivation, as assessed by questionnaires. <br>

Secondary Outcome Measures

Name	Time	Method
Preliminary effectiveness is assessed by measuring physical functioning (timed up and go test, hand grip strength, walking speed/ six-minute walk test, chair rise time test, questionnaires), body composition (BIA/ DEXA) and inflammation (CRP, IL-6) before and after 6 weeks of intervention. In addition, postoperative inpatient complications, recovery of physical functioning and length of hospital stay will be assessed.<br>Furthermore, nutritional intake (3-day food diary) and physical activity (by accelerometer) will be measured.<br>