Cerebral networks involved in internal scaling of spatial dimensions.
- Conditions
- Gezonde populatieHealthy population
- Registration Number
- NL-OMON38588
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 16
Healthy right-handed persons aged 18-65 years.
Subjects who suffer from specific neurological or psychiatric disorders or injury to the upper extremities will be excluded. Subjects who cannot go in the MRI scanner are also excluded. With neurological disorders we mean disorders for which the consult of a medical specialist was necessary: epilepsia, severe brain injury and temporary paralysis. Exclusion criteria for the MRI are for example the presence of ferromagnetic material in or on the body, pregnancy or claustrophobia. (specifief in the questionnaire) Furthermore, subjects who are right-handed, but draw with their left hand are excluded. Also, subjects with an uncorrectable abnormality in visual acuity will be excluded.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Localisation of condition-related increase in cerebral activation in the medial<br /><br>and lateral premotor cortex. A voxel-based analysis of task-related cerebral<br /><br>activation (increased BOLD responses) will be performed using 'Statistical<br /><br>Parametric Mapping' (SPM8). In this way differences in medial and lateral<br /><br>premotor cortex activation between the different experimental conditions will<br /><br>be quantified. The number of 16 subjects is enough for a random effects<br /><br>analysis of the fMRI data.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable.</p><br>