Single Administration study of Bomedemstat (MK-3543) in Healthy Japanese
Phase 1
Recruiting
- Conditions
- Essential thrombocythaemia
- Registration Number
- JPRN-jRCT2071230096
- Lead Sponsor
- Tanaka Yoshiyuki
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
1) Be in good health based on medical history, physical examination, vital sign measurements, 12-lead ECGs at the Screening Visit and before administration of the dose of the study intervention.
2) BMI >= 18.5 and <= 32.0 kg/m2, inclusive, with a body weight >= 50 and <= 100 kg.
3) Is an individual of any sex/gender, from 18 years to 64 years of age inclusive, at the time of providing the informed consent.
Exclusion Criteria
1) History of clinically significant endocrine, GI, cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological (including stroke and chronic seizures) abnormalities or diseases.
2) History of cancer (malignancy).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method MK-3543 PK
- Secondary Outcome Measures
Name Time Method Adveres event