Effect of early postextubation high flow nasal cannula vs conventional low flow oxygen therapy on reintubation in postoperative patients from prolonged general anesthesia at surgical ICU: A Randomized Clinical Trial

Phase 2

Recruiting

• Conditions: Postoperative patients from prolonged general anesthesia at surgical ICU; High flow nasal cannula Reintubation; Postoperative patients Prolonged general anesthesia; Intensive care unit

• Registration Number: TCTR20220805002
• Lead Sponsor: Siriraj hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-08-05
• Study Completion: 2023-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 260

Inclusion Criteria

All adult patients scheduled for non cardiothoracic surgery
All adult patients scheduled for non neurosurgery
An anticipated general anesthesia duration of 4 h or more
A moderate to high risk of postoperative pulmonary complications
ASA classification at least 2
Postoperative observation at surgical ICU

Exclusion Criteria

Body mass index greater than 35
Life threatening condition requiring emergency surgery
Obstructive sleep apnea syndrome
Pregnancy
Tracheostomy patients
Contraindicated in using HFNC after extubation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reintubation 72 hours Rate

Secondary Outcome Measures

Name	Time	Method
postoperative pulmonary complications 7 days grade,ICU length of stay 30 days Days,Hospital length of stay 90 days Days,Mortality 90 days Rate