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Comparison of the effects of two breathing aids, the high-flow nasal cannula and the venturi mask, on exercise tolerance in lung transplant candidates

Not Applicable
Conditions
ung Diseases
Registration Number
RBR-10gqsbsm
Lead Sponsor
Hospital de Messejana Dr Carlos Alberto Studart Gomes
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Data analysis completed
Sex
Not specified
Target Recruitment
Not specified
Inclusion Criteria

Lung transplant candidates; both genders; older than 18 years; in initial evaluation for inclusion in a pulmonary rehabilitation program; with oxygen dependency or need for oxygen supplementation during the symptom-limited incremental load test performed before inclusion in the study

Exclusion Criteria

Candidates who did not comply with the protocol, because they were absent on the assessment day; candidates who did not present clinical conditions on the day of the test

Study & Design

Study Type
Intervention
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Outcome found 1: A difference of 357 s (95% confidence interval – CI 181 – 533 s; p = 0.001) was found in exercise tolerance between the time achieved in the endurance test performed with the high-flow nasal cannula (937 s, 95% CI 668 – 1205 s) and the time achieved in the endurance test performed with the Venturi mask (580 s, 95% CI 403 – 756 s).;Expected outcome 1: It is expected to find a difference of at least 109 seconds in exercise tolerance between the time achieved in the endurance test performed with the high-flow nasal cannula and the time achieved in the endurance test performed with the Venturi mask.
Secondary Outcome Measures
NameTimeMethod
Expected outcome 2: Absence of difference in the comparison of changes between pre- and post-endurance test, in physiological variables such as symptoms of dyspnea and lower limb fatigue, respiratory rate, peripheral oxygen saturation, heart rate, blood pressure and peripheral blood lactate level , between the two oxygen systems (high-flow nasal cannula and Venturi mask).;Outcome found 2: There was no statistically significant or clinically important difference in the comparison of changes between pre- and post-endurance test, in physiological variables such as symptoms of dyspnea and lower limb fatigue, respiratory rate, peripheral oxygen saturation, heart rate, blood pressure and peripheral blood lactate level, between the two oxygen systems (high-flow nasal cannula and Venturi mask).
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