Comparative study of high flow nasal cannula and non invasive ventilation in patients with pneumonia.
Phase 2
- Conditions
- Health Condition 1: J960- Acute respiratory failureHealth Condition 2: J189- Pneumonia, unspecified organism
- Registration Number
- CTRI/2024/08/071774
- Lead Sponsor
- KP Salve Institure of Medical Sciences and Research Centre and Lata Mangeshkar Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with moderate to severe pneumonia (CURB65 more than 2) requiring oxygenation (PaO2/FiO2 less than 300) (PaO2 less than 60).
Patints more than 18 years of age.
Exclusion Criteria
Patients having contraindications of HFNC and NIV.
Patients requiring mechanical ventilation.
Patients not giving consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Improvement in PaO2/FiO2 <br/ ><br>2. Improvement in PaO2 <br/ ><br>3.Improvement in Respiratory rate <br/ ><br>4. Improvement in SpO2Timepoint: 1. Improvement in PaO2/FiO2 after 72 hours of HFNC/ NIV <br/ ><br>2. Improvement in PaO2 after 72 hours of HFNC / NIV <br/ ><br>3.Improvement in Respiratory rate after 72 hours of HFNC / NIV <br/ ><br>4. Improvement in SpO2
- Secondary Outcome Measures
Name Time Method To study efficacy of NIV and HFNC in patients with moderate to severe pneumonia. <br/ ><br>2. To study compliance of NIV and HFNC in patients.Timepoint: From application till 72 hours.