A comparative study of two modes of ventilation in Chronic Obstructive Lung Disease
Phase 3
- Conditions
- Health Condition 1: J439- Emphysema, unspecified
- Registration Number
- CTRI/2023/04/051659
- Lead Sponsor
- Srinath S
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients with acute exacerbation of Chronic Obstructive Pulmonary Disease with Moderate Respiratory Failure PCO2:45-65mmHg;pH:7.25-7.35
Exclusion Criteria
1.Patients who are having Type I respiratory failure
2.Massive aspiration
3.Persistent inability to remove respiratory secretions
4.Inability to tolerate NIV BIPAP/NIV BIPAP failure
5.Status post respiratory or cardiac arrest
6.Severe ventricular or supraventricular arrhythmias
7.Patient who got neck and face trauma
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy of High Flow Nasal Cannula with Non Invasive Ventilation Bilevel Positive Airway Pressure in Acute exacerbation of Chronic Obstructive Pulmonary Disease by clinical parameters and Arterial Blood Gas AnalysisTimepoint: Arterial Blood Gas analysis at 2 and 6 hours after initiation of therapy
- Secondary Outcome Measures
Name Time Method To compare the efficacy of High Flow Nasal Cannula with Non Invasive Ventilation Bilevel Positive Airway Pressure in Acute exacerbation of Chronic Obstructive Pulmonary Disease in terms of patient comfort and adherence to treatmentTimepoint: To assess patient comfort and adherence to treatment after the end of therapy