Optimal postoperative chest tube and pain management in patients surgically treated for primary spontaneous pneumothorax; a randomized controlled trial. - Pneumotrial

Maxima Medisch Centrum0 个研究点目标入组 340 人开始时间: 待定最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•- Patients with primary spontaneous pneumothorax (PSP) and referred for surgery
•due to recurrence, prolonged air leak (>=5 days), accompanied hemothorax or a
•profession at risk (diving, polar explorers, working with compressed air). -
•Age >= 16 years - Able to read and understand the Dutch language - Mentally able
•to provide informed consent - Patients should have a preoperative chest CT scan
•in order to exclude evident secondary pneumothorax. Previously made CT scans,
•within a time range of maximum 5 years, are accepted.

•- Previous ipsilateral thoracic surgery (except diagnostic thoracoscopy only)
•or ipsilateral thoracic radiotherapy
•- Underlying lung disease that provoked the pneumothorax (secondary
•pneumothorax): genetically proven Birt-Hogg-Dubé syndrome, periodic
•pneumothorax in female patients in reproductive age with known endometriosis
•(or known catamenial pneumothorax), pulmonary cystic fibrosis, lungfibrosis,
•chronic obstructive pulmonary disease (COPD), active pneumonia, pulmonary
•ipsilateral malignancy
•- Contra-indications for thoracic epidural analgesia (TEA) (infection at skin
•site, increased intracranial pressure, non-correctable coagulopathy, sepsis and
•mechanical spine obstruction)
•- Patients chronically using opioids will be excluded since postoperative
•baseline opioid requirement will be higher and TEA remains the preferred
•technique for these patients
•- Allergic reactions to analgesics used in the study

发起方

Maxima Medisch Centrum