Effects of Aerobic and Resistance Training on Abdominal Fat Loss
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- Changes in Visceral Abdominal Tissue (VAT)
研究概览
简要总结
Study the effects of different exercise modes on total and regional adiposity variation in subcutaneous and visceral adipose tissue (VAT and SAT). The investigators hypothesize that total abdominal will improve for all the exercise groups compared to the control group. When comparing intervention groups: 1) no differences on the degree of improvement in total abdominal fat depots (VAT and SAT) 2) different degree of change when comparing specific sections at VAT and SAT are expected.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •30 - 39.9 kg/m2 BMI
- •White/Caucasian
- •Sedentary
排除标准
- •Known cardiovascular, pulmonary, metabolic disease
- •Pregnant females
- •Any excluded criteria with MRI scans (i.e. certain metal implants, recent tattoos)
- •Hypertension
- •Cigarette smoking
- •MRI related contraindications (metal, no removable devices, etc.)
研究组 & 干预措施
Resistance Training Group
Resistance training will consist of 3 whole body circuits per week for 3 weeks lasting approximately 1 hour per session. All major muscle groups will be involved (leg press, bent-over-row, bench press, back squat, dumbbell jump squats, dead-lifts, and weighted abdominal crunches). Each participant will go through each circuit three times with 30 seconds between each exercise and 2 minutes between each set.
干预措施: Resistance Training (Other)
Aerobic Training Group
Aerobic interval training will consist of 3 sessions/week for 3 weeks for approximately 45-50 minutes per session depending on exercise energy expenditure. There will be two periods of intervals. The first period will be 3 minutes of high-intensity activity and the second period will be reduced to moderate-intensity for 2 minutes. The speed/incline will change depending on the participants perception or Borg's rating of perceived exertion. Intensity will be measured using Lactate levels after each session.
干预措施: Aerobic Training (Other)
Control Group
The control group must attend sessions but will not exercise.
结局指标
主要结局
Changes in Visceral Abdominal Tissue (VAT)
时间窗: 2 assessment periods: at baseline and week 4
Changes in VAT will be measured using Magnetic Resonance Imaging
次要结局
- Changes in concentration of TNF-alpha(2 assessment periods: at baseline and week 4)
- Changes in relative body fat (%BF)(2 assessment periods: at baseline and week 4)
- Changes in Muscular Strength(2 assessment periods: at baseline and week 4)
- Changes in Cardiorespiratory Function(2 assessment periods: at baseline and week 4)
- Changes in Lipid profile (TG, Total Cholesterol, HDL2 HDL3, LDL)(2 assessment periods: at baseline and week 4)
- Changes in concentration of Troponin(2 assessment periods: at baseline and week 4)
- Changes in Subcutaneous Abdominal Tissue (SAT)(2 assessment periods: at baseline and week 4)
- Changes in relative lean body mass (kg)(2 assessment periods: at baseline and week 4)
- Changes in concentration of IL-6(2 assessment periods: at baseline and week 4)
- Changes in concentration of IL-10(2 assessment periods: at baseline and week 4)
- Changes in concentration of Fibrinogen(2 assessment periods: at baseline and week 4)
- Changes in fat mass (kg)(2 assessment periods: at baseline and week 4)
- Changes in concentration of C-reactive protein (CRP)(2 assessment periods: at baseline and week 4)