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临床试验/NCT05328570
NCT05328570已完成不适用

Effects of Exercise Training on the Structure and Metabolic Function of Fat Tissue

University of Michigan2 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2020年6月4日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
45
试验地点
2
主要终点
Adipose tissue fibrosis

研究概览

简要总结

Assess differences in structure and biological function of abdominal subcutaneous adipose tissue samples collected from adults who exercise regularly vs. a well-matched cohort of non-exercisers.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Age: 18-40 years old
  • Body Mass Index: 23-35 kg/m2
  • Women must have regularly occurring menses and must be premenopausal

排除标准

  • Evidence/history of cardiovascular or metabolic disease
  • Medications known to affect lipid or glucose metabolism, or inflammation
  • Weight instability ≥ ± 6 pounds in the last 6 months
  • Tobacco or e-cigarette users
  • Women must not be pregnant or actively lactating
  • Blood pressure > 140/90 mmHg

结局指标

主要结局

Adipose tissue fibrosis

时间窗: baseline

Pico-sirius Red stain (percent stained)

Blood Glucose Level

时间窗: 2 hours at Experimental Trial

mg/dL

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jeffrey F Horowitz

Professor of Movement Science and Director of the Substrate Metabolism Laboratory (SML) at the University of Michigan School of Kinesiology

University of Michigan

研究点 (2)

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