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Comparing the Effects of Exercise on the Structure and Function of Fat Tissue

Not Applicable
Completed
Conditions
Adiposity
Registration Number
NCT05328570
Lead Sponsor
University of Michigan
Brief Summary

Assess differences in structure and biological function of abdominal subcutaneous adipose tissue samples collected from adults who exercise regularly vs. a well-matched cohort of non-exercisers.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
45
Inclusion Criteria
  • Age: 18-40 years old
  • Body Mass Index: 23-35 kg/m2
  • Women must have regularly occurring menses and must be premenopausal
Exclusion Criteria
  • Evidence/history of cardiovascular or metabolic disease
  • Medications known to affect lipid or glucose metabolism, or inflammation
  • Weight instability ≥ ± 6 pounds in the last 6 months
  • Tobacco or e-cigarette users
  • Women must not be pregnant or actively lactating
  • Blood pressure > 140/90 mmHg

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Adipose tissue fibrosisbaseline

Pico-sirius Red stain (percent stained)

Blood Glucose Level2 hours at Experimental Trial

mg/dL

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

University of Michigan

🇺🇸

Ann Arbor, Michigan, United States

University of Michigan
🇺🇸Ann Arbor, Michigan, United States

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