Effects of Aerobic and Resistance Training on Abdominal Fat Loss
- Conditions
- Obesity, Abdominal
- Interventions
- Other: Resistance TrainingOther: Aerobic Training
- Registration Number
- NCT03700827
- Lead Sponsor
- Southern Illinois University Edwardsville
- Brief Summary
Study the effects of different exercise modes on total and regional adiposity variation in subcutaneous and visceral adipose tissue (VAT and SAT). The investigators hypothesize that total abdominal will improve for all the exercise groups compared to the control group. When comparing intervention groups: 1) no differences on the degree of improvement in total abdominal fat depots (VAT and SAT) 2) different degree of change when comparing specific sections at VAT and SAT are expected.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- Female
- Target Recruitment
- 18
- 30 - 39.9 kg/m2 BMI
- White/Caucasian
- Female
- Sedentary
- Known cardiovascular, pulmonary, metabolic disease
- Pregnant females
- Any excluded criteria with MRI scans (i.e. certain metal implants, recent tattoos)
- Diabetic
- Hypertension
- Cigarette smoking
- MRI related contraindications (metal, no removable devices, etc.)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Resistance Training Group Resistance Training Resistance training will consist of 3 whole body circuits per week for 3 weeks lasting approximately 1 hour per session. All major muscle groups will be involved (leg press, bent-over-row, bench press, back squat, dumbbell jump squats, dead-lifts, and weighted abdominal crunches). Each participant will go through each circuit three times with 30 seconds between each exercise and 2 minutes between each set. Aerobic Training Group Aerobic Training Aerobic interval training will consist of 3 sessions/week for 3 weeks for approximately 45-50 minutes per session depending on exercise energy expenditure. There will be two periods of intervals. The first period will be 3 minutes of high-intensity activity and the second period will be reduced to moderate-intensity for 2 minutes. The speed/incline will change depending on the participants perception or Borg's rating of perceived exertion. Intensity will be measured using Lactate levels after each session.
- Primary Outcome Measures
Name Time Method Changes in Visceral Abdominal Tissue (VAT) 2 assessment periods: at baseline and week 4 Changes in VAT will be measured using Magnetic Resonance Imaging
- Secondary Outcome Measures
Name Time Method Changes in relative body fat (%BF) 2 assessment periods: at baseline and week 4 Changes in body composition (relative body fat, lean body mass and fat mass) will be measured using dual-energy x-ray absorptiometry
Changes in Cardiorespiratory Function 2 assessment periods: at baseline and week 4 Changes in cardiorespiratory will measured on a treadmill with a metabolic cart
Changes in Lipid profile (TG, Total Cholesterol, HDL2 HDL3, LDL) 2 assessment periods: at baseline and week 4 Samples will be processed to obtain serum and plasma, and stored at -80°c until analysis
Changes in concentration of Troponin 2 assessment periods: at baseline and week 4 Will be performed using a Luminex MAGPIX System with xPONENT 4.2
Changes in Muscular Strength 2 assessment periods: at baseline and week 4 Changes in muscular strength will be assessed by one-repetition maximum test on leg press and bench press
Changes in Subcutaneous Abdominal Tissue (SAT) 2 assessment periods: at baseline and week 4 Changes in SAT will be measured using Magnetic Resonance Imaging
Changes in relative lean body mass (kg) 2 assessment periods: at baseline and week 4 Changes in lean body mass will be measured using dual-energy x-ray absorptiometry
Changes in concentration of IL-6 2 assessment periods: at baseline and week 4 Will be performed using a Luminex MAGPIX System with xPONENT 4.2
Changes in concentration of IL-10 2 assessment periods: at baseline and week 4 Will be performed using a Luminex MAGPIX System with xPONENT 4.2
Changes in concentration of Fibrinogen 2 assessment periods: at baseline and week 4 Will be performed using a Luminex MAGPIX System with xPONENT 4.2
Changes in fat mass (kg) 2 assessment periods: at baseline and week 4 Changes in fat mass will be measured using dual-energy x-ray absorptiometry
Changes in concentration of C-reactive protein (CRP) 2 assessment periods: at baseline and week 4 Will be performed using a Luminex MAGPIX System with xPONENT 4.2
Changes in concentration of TNF-alpha 2 assessment periods: at baseline and week 4 Will be performed using a Luminex MAGPIX System with xPONENT 4.2
Trial Locations
- Locations (1)
Southern Illinois University of Edwardsville
🇺🇸Edwardsville, Illinois, United States