跳至主要内容
临床试验/CTRI/2021/03/032041
CTRI/2021/03/032041尚未招募不适用

Comparing the efficacy of Pericapsular nerve group block (PENG) block versus Supra-inguinal fascia iliaca block (FIB) in Total Hip Arthroplasty : A prospective randomized control trial.

Not funded1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2021年3月24日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
24-hour morphine consumption.

研究概览

简要总结

The current modalities for pain control often rely on multimodal analgesia. Opioids remain an integral part of most analgesic plans either via intravenous boluses, infusion or patient controlled analgesia (PCA) pumps. Using opioids alone intensifies their side-effect profile that includes, postoperative nausea and vomiting (PONV), sedation, pruritus and respiratory depression.The common opioid sparing methods are use of non-steroidal anti inflammatory drugs (NSAIDs), spinal opioids, epidural postoperative analgesia and peripheral nerve blockade3.Peripheral nerve blockade has started gaining attention in the recent past for arthroplasty. Although its place is well recognized in knee arthroplasty its place in hip arthroplasty is not well defined. The modified supra inguinal approach of FIB described by Stevens places the local anaesthetic (LA) solution in the fascia iliaca plane higher up than the conventional technique and thus allow more superior spread of  (LAs) and hence blockade of nerves derived from L1 and L2 anterior rami of lumbar plexus (ilioinguinal, iliohypogastric and genitofemoral) leading to more effective pain relif. 5We The anterior capsule is the most richly innervated section of the joint suggesting these nerves should be the main targets for hip analgesia. A recent anatomical study by Short et al15 confirmed the innervation of the anterior hip by these 3 main nerves but also found that the AON and FN play a greater role in the anterior hip innervation than previously reported. The hypothesis of this study is that a PENG block will provide a better postoperative analgesia and reduce opioid consumption in the postoperative period in patients undergoing THR.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
25.00 Year(s) 至 75.00 Year(s)(—)
性别
All

入选标准

  • Patients scheduled for elective Total Hip arthroplasty.
  • ASA I and II including both the sexes.
  • Age group: 25 to 75 years.

排除标准

  • ASA III / IV ​
  • Patient refusal to take part in the study
  • Morbid obesity (BMI ≥ 40) 4.History of focal neurological deficit 5.History of sensory or motor disorders of limb to be operated
  • History of allergy to local anaesthetics, clonidine
  • History of regular opioid use
  • Infection at puncture site for both approaches of block .
  • Inability to understand the use of PCA device.

结局指标

主要结局

24-hour morphine consumption.

时间窗: 24-hour morphine consumption.

次要结局

  • Intraoperative opioid consumption(•Mean Numerical rating scale[NRS]in 24 hours)

研究者

发起方
Not funded
申办方类型
Other [nil]

研究点 (1)

Loading locations...

相似试验