KCT0004325招募中未知
Effects of high-dose STatin versus low-dose statin plus ezetimibe On coronary atherosclerotic Plaques in patients with stable Coronary Artery Disease (StopCAD trial)
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 300
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 19(Year) 至 0No Limit（—）
- 性别
- All
入选标准
- •Participants in this study should meet all of the following selection criteria.
- •1) Those who are 18 years of age or older on the consent date
- •2) Stable coronary artery disease with moderate or more significant stenosis in the main coronary artery on CT (> 50% internal stenosis).
- •3) Patients or agents who have agreed to the study plan and clinical and coronary computed tomography follow-up, and have previously agreed in writing to the clinical trial subject autonomy approved by the research institution's research review committee / ethics committee.
排除标准
- •Exclusion Criteria for Clinical Subjects
- •Subjects who meet any of the following exclusion criteria cannot participate in this study.
- •1) unstable angina or acute myocardial infarction
- •2) If you have undergone coronary stent surgery or coronary artery bypass surgery
- •3) If you have chronic kidney disease (eGFR <60ml / min)
- •4) Cardiac surgery or major surgery is planned within the last 6 months
- •5) Patients with chronic diseases such as cirrhosis, severe lung disease, hard stroke
- •6) Patients with chronic inflammatory diseases requiring oral, intravenous or intraarticular steroid treatment
- •(Ointments, inhalants, or intranasal steroids are allowed.)
- •7) Have been diagnosed with cancer (except superficial squamous cell / basal cell skin cancer) within the past 3 years or currently undergoing chemotherapy
- •8) There are clinically significant abnormal findings that may violate the safety of the study by the investigator's judgment confirmed by screening visit, physical examination, blood test or ECG test.
- •9) Hepatic insufficiency or cholestatic obstruction or liver enzyme level (ALT / AST) is more than three times normal
- •10) You have a history of asthma from bronchial spasms within the last 6 months or you are currently taking regular anti-asthma medicine
- •11) If you have a disease with a life expectancy of 2 years or less
- •12) If the procedures described in the protocol are not desired or cannot be followed.
- •13) Pregnant women, lactating women, women of childbearing age who do not use reliable contraceptive methods or who do not agree to maintain contraception during clinical trials.
研究者
相似试验
招募中
不适用
The effect of high dose statins (Simvastatin 80 mg) on vascular inflammation in the abdominal aneurysm.Abdominal Aortic AneurysmNL-OMON24165eiden University Medical Center25
已完成
不适用
Effects of high-dose StAtin Versus low-dose statin plus Ezetimibe on Statin-Associated Muscle Symptoms & on reaching target LDL-C levels among elderly patients with atherosclerotic cardiovascular disease (SaveSAMS trial)KCT0006265Korea University Anam Hospital582
尚未招募
不适用
The effect of high dose statin therapy (Simvastatin 80 mg) on vascular inflammation in the aortic abdominal aneurysm.Abdominal Aortic AneurysmNL-OMON2514625
招募中
不适用
Effects of statin medication and cardiovascular disease on pulp chamber calcification - A 3-dimensional radiographic analysis on Indian populatioCTRI/2024/06/069197eha
已完成
4 期
Effects of Statin for Elderly Patients With Atherosclerotic Cardiovascular DiseaseAtheroscleroses, CoronaryNCT04826354Korea University Anam Hospital582