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临床试验/KCT0004325
KCT0004325招募中未知

Effects of high-dose STatin versus low-dose statin plus ezetimibe On coronary atherosclerotic Plaques in patients with stable Coronary Artery Disease (StopCAD trial)

Kangbuk Samsung Medical Center0 个研究点目标入组 300 人开始时间: 待定最近更新:

试验速览

阶段
未知
状态
招募中
入组人数
300

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional Study

入排标准

年龄范围
19(Year) 至 0No Limit(—)
性别
All

入选标准

  • Participants in this study should meet all of the following selection criteria.
  • 1) Those who are 18 years of age or older on the consent date
  • 2) Stable coronary artery disease with moderate or more significant stenosis in the main coronary artery on CT (> 50% internal stenosis).
  • 3) Patients or agents who have agreed to the study plan and clinical and coronary computed tomography follow-up, and have previously agreed in writing to the clinical trial subject autonomy approved by the research institution's research review committee / ethics committee.

排除标准

  • Exclusion Criteria for Clinical Subjects
  • Subjects who meet any of the following exclusion criteria cannot participate in this study.
  • 1) unstable angina or acute myocardial infarction
  • 2) If you have undergone coronary stent surgery or coronary artery bypass surgery
  • 3) If you have chronic kidney disease (eGFR <60ml / min)
  • 4) Cardiac surgery or major surgery is planned within the last 6 months
  • 5) Patients with chronic diseases such as cirrhosis, severe lung disease, hard stroke
  • 6) Patients with chronic inflammatory diseases requiring oral, intravenous or intraarticular steroid treatment
  • (Ointments, inhalants, or intranasal steroids are allowed.)
  • 7) Have been diagnosed with cancer (except superficial squamous cell / basal cell skin cancer) within the past 3 years or currently undergoing chemotherapy
  • 8) There are clinically significant abnormal findings that may violate the safety of the study by the investigator's judgment confirmed by screening visit, physical examination, blood test or ECG test.
  • 9) Hepatic insufficiency or cholestatic obstruction or liver enzyme level (ALT / AST) is more than three times normal
  • 10) You have a history of asthma from bronchial spasms within the last 6 months or you are currently taking regular anti-asthma medicine
  • 11) If you have a disease with a life expectancy of 2 years or less
  • 12) If the procedures described in the protocol are not desired or cannot be followed.
  • 13) Pregnant women, lactating women, women of childbearing age who do not use reliable contraceptive methods or who do not agree to maintain contraception during clinical trials.

研究者

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