The benefit of ultra-high resolution computed tomography: Precision of repeated volume measurements of pulmonary nodules
- Conditions
- Lung Mestastase - Lung cancer1003866610037454
- Registration Number
- NL-OMON45824
- Lead Sponsor
- Radboud Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
* 18 years of age or older
* A solid primary tumour anywhere in the body and solid, noncalcified nodules in the pulmonary parenchyma on previous CT scans suspected for pulmonary metastases, according to radiological reports
* Two lung nodules that do not abut vessels or pleura with a two dimensional diameter between 5 and 10 mm within a distance of each other of 16 cm in the craniocaudal direction
* Immobility (not able to stand up and get off the scanner table)
* Patients who received local pulmonary treatment:
o Radiotherapy
o Excision
o Ablation
* Patients with radiologically suspected lymphangitis carcinomatosa or consolidations around the nodules.
* Patients who only have calcified pulmonary nodules or nodules that about vessels or pleura.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main endpoint of this study is the upper limit of the 95% confidence<br /><br>interval of repeated semi-automated nodule volume measurements of both CT<br /><br>scanners. </p><br>
- Secondary Outcome Measures
Name Time Method <p>* To assess the variability in manual calliper two-dimensional measurements of<br /><br>pulmonary nodules.<br /><br>* To assess the effect of subjective image quality, structure delineation and<br /><br>segmentation, and nodule type on the variability in volume of the nodule<br /><br>measurements.</p><br>