Study on Left Atrial Function of Paroxysmal Supraventricular Tachycardia After Radiofrequency Ablation

Not Applicable

Completed

• Conditions: Paroxysmal Supraventricular Tachycardia
• Interventions: Procedure: radiofrequency ablation

• Registration Number: NCT03348436
• Lead Sponsor: Ruiqin xie

Brief Summary

This study to investigate the effects of RF ablation on left atrial systolic function in patients with atrioventricular nodal reentrant tachycardia (AVNRT) and atrioventricular tachycardia (AVRT).

Detailed Description

A total of 100 patients with persistent，in whom successful RF ablation of slow pathway or accessory pathway was performed. Patients with atrial fibrillation, structural heart disease, ventricular arrhythmias, impaired left ventricular systolic function or on antiarrhythmics were excluded. All the patients had echocardiographic study before ablation 、1 day and 1 months after ablation. Left atrial systolic function was assessed using atrial ejection force (AEF) according to Manning's formula (AEF = 0.5 x ρ x MA x A(2), r: blood density = 1.06 g/cm(3), MA: mitral orifice area \[cm(2)\], A: A wave velocity). The following left atrial dimensions were assessed: antero-posterior (LA-AP), infero-superior (LA-IS, long axis), medio-lateral (LA-ML, short axis). The correlations between AEF and electrophysiological parameters were analysed (VA - ventriculo-atrial conduction, VA/CL - tachycardia cycle length).

Study Timeline

• Study Start: 2017-01-01
• Study First Submitted: 2017-11-16
• Study First Submitted QC: 2017-11-17
• Study First Posted: 2017-11-20
• Status Verified: 2020-03
• Primary Completion: 2020-03-01
• Study Completion: 2020-03-01
• Last Update Submitted: 2020-03-17
• Last Update Posted: 2020-03-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients with paroxysmal supraventricular tachycardia,includes atrioventricular reentrant tachycardia and atrioventricular nodal reentrant tachycardia， Age is >14 years

Exclusion Criteria

Atrial fibrillation, Atrial tachycardia， Structural heart disease, Ventricular arrhythmias, Patients with impaired left ventricular systolic function or on antiarrhythmics

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
patients with atrioventricular nodal reentrant tachycardia	radiofrequency ablation	radiofrequency catheter ablation therapy
patients with atrioventricular tachycardia	radiofrequency ablation	radiofrequency catheter ablation therapy

Primary Outcome Measures

Name	Time	Method
Left Atrial Function of postoperative radiofrequency ablation.	1 month

Trial Locations

Locations (1)

The Second Hospital of Hebei Medical University; 🇨🇳 Shijiazhuang, Hebei, China