Comparison between two anaesthetic drugs Propofol and Ketamine during anaesthesia in Electro Convulsive Therapy in treatment of depressive disorders.

Not yet recruiting

• Conditions: Major depressive disorder, recurrent, severe with psychotic symptoms,

• Registration Number: CTRI/2019/05/018890
• Lead Sponsor: Armed Forces Medical College

Brief Summary

This study is a prospective, single blind, randomized control trial comparing the effects of Propofol and Ketamine in modified ECT which will be conducted in a tertiary care hospital in India. The ECT sessions will be randomized in two groups of 22 each. The first group will be given Propofol as the induction agent and the second group will be given Ketamine as the induction agent. As per their randomization each patient will be given inj Propofol 1.5 mg/kg iv or inj Ketamine 0.8-1.2 mg/kg iv. The primary objective will be comparison of duration of seizure (both motor and EEG) between Propofol and Ketamine.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2019-04-30
• Study Start: 2019-05-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

All patients of age more than 18 yrs scheduled for ECT.

Exclusion Criteria

• Patients not giving consent 2.
• Raised intracranial pressure 3.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
comparison of Duration of seizure (both motor and EEG) between Propofol and Ketamine when used in modified ECT	outcome will be assessed immediately after administering the drug till the time the seizure will last.

Trial Locations

Locations (1)

Armed Force Medical College; 🇮🇳 Pune, MAHARASHTRA, India

Armed Force Medical College

🇮🇳Pune, MAHARASHTRA, India

Dr Debarshi Guha

Principal investigator

8879526556

drdebarshi.guha@gmail.com