Impact of Visceral Fat on the Pathogenesis of Age-related Macular Degeneration

• Conditions: Age-related Macular Degeneration

• Registration Number: NCT01777984
• Lead Sponsor: Rudolf Foundation Clinic

Brief Summary

The purpose of this study is to determine the relationship among the body fat distribution, especially the visceral fat, in patients with age-related macular degeneration in comparison to patients with a normal fundus.

Detailed Description

In this study the investigators want to examine the relationship among visceral fat, serum leptin levels, and high-sensitive CRP (hsCRP), Tnf-alpha, Amyloid alpha and Amyloid Beta serum levels in patients with age-related macular degeneration in comparison to patients with a normal fundus.

Study Timeline

• Study Start: 2009-12
• Study First Submitted: 2011-12-01
• Status Verified: 2013-01
• Study First Submitted QC: 2013-01-24
• Last Update Submitted: 2013-01-24
• Study First Posted: 2013-01-29
• Last Update Posted: 2013-01-29
• Primary Completion: 2013-05
• Study Completion: 2013-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• man and women over 18 years old
• filled informed consent
• diagnosis of age-related macular degeneration

Exclusion Criteria

• inherited retinal disease
• other acquired retinal macular disease
• missing informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
visceral fat ratio	1 day

Secondary Outcome Measures

Name	Time	Method
Leptin, Amyloid, TNF alpha, CRP	1 day

Trial Locations

Locations (1)

Rudolf Foundation Clinic; 🇦🇹 Vienna, Austria