KCT0007801Completed未知
Finding 50% effective dose of remimazolam for facilitating I-gel insertion with remifentanil target-controlled infusion
Ajou University Hospital0 sites25 target enrollmentStarted: TBDLast updated:
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Enrollment
- 25
Study Overview
Brief Summary
The remimazolam bolus dose for successful I-gel insertion in 50% of adult patients with Ce 3.0 ng/mL of remifentanil and without NMBAs was 0.280 ± 0.048 mg/kg. From the isotonic regression analysis, ED50 and ED95 were 0.244 (83% CI 0.213–0.313) mg/kg and 0.444 (95% CI 0.436–0.448) mg/kg, respectively.
Study Design
- Study Type
- Interventional Study
Eligibility Criteria
- Ages
- 19(Year) to 65(Year) (—)
- Sex
- All
Inclusion Criteria
- •Adult patients aged 19-65 years with ASA score 1 or 2 scheduled for general anesthesia and eligible for I-gel use
Exclusion Criteria
- •BMI > 30 kg/m2
- •Patient refusal
- •Anticipated difficult airway
- •Anticipated difficult mask ventilation
- •COPD, astham, pneumonia, active URI
- •Risk of aspiration
- •Patients unable to response on verbal command
- •History of allergies to benzodiazepines
- •History of allergies to opioids
- •History of substance abuse/addiction
- •Pregnant or breastfeeding patients
Investigators
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