Dose of Remi in Children

Not Applicable

Not yet recruiting

• Conditions: Anesthesia
• Interventions: Drug: Remimazolam

• Registration Number: NCT05990673
• Lead Sponsor: Zhihong LU

Brief Summary

Remimazolam has demonstrated the potential as a valuable medication for procedural sedation and general anesthesia. However, the effective dosage of remimazolam in pediatric patients is still unknown.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-08
• Study First Submitted: 2023-08-07
• Study First Submitted QC: 2023-08-07
• Last Update Submitted: 2023-08-07
• Study Start: 2023-08-10
• Study First Posted: 2023-08-14
• Last Update Posted: 2023-08-14
• Primary Completion: 2023-09-10
• Study Completion: 2023-09-10

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• age from 3 to 12 years old
• patients scheduled for surgery under general anesthesia

Exclusion Criteria

• American Society of Anesthesiologists status >=Ⅲ
• Body mass index>=28kg/m2
• patients who cannot cooperate with intravenous anesthesia induction
• patients with risk of difficult airway
• patients who are allergic to benzodiazepines
• patients with delayed neurologic function

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SEQUENTIAL

Arm && Interventions

Group	Intervention	Description
remimazolam	Remimazolam	remimazolam is given for anesthesia induction

Primary Outcome Measures

Name	Time	Method
half effective dosage	from injection of remimazolam to loss of consciousness, at an average of 5 minutes	the dosage by which half of the patients will be sedated

Secondary Outcome Measures

Name	Time	Method
95% effective dosage	from injection of remimazolam to loss of consciousness, at an average of 5 minutes	the dosage by which 95% of the patients will be sedated