Right Ventricular Hypertrophy After Atrial Switch and Cardiovascular Magnetic Resonance (CMR) Findings

Completed

• Conditions: Right Ventricular Hypertrophy; d-TGA

• Registration Number: NCT01430897
• Lead Sponsor: University of Leipzig

Brief Summary

Systemic RV hypertrophy and impaired systolic function occur after atrial switch (AS) in d-transposition of the great arteries (d-TGA). Echocardiography has limitation in the assessment of the right ventricle (RV).

In this study the investigators sought to evaluate systemic RV myocardial mass and function after AS for d-TGA and to analyze the role of excessive hypertrophy for ventricular function under special consideration of the interventricular septal (IVS) movement.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-04
• Primary Completion: 2011-04
• Status Verified: 2011-09
• Study Completion: 2011-09
• Study First Submitted: 2011-09-05
• Study First Submitted QC: 2011-09-07
• Last Update Submitted: 2011-09-07
• Study First Posted: 2011-09-08
• Last Update Posted: 2011-09-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 37

Inclusion Criteria

• Eligibility criteria were an AS operation in childhood for correction of d-TGA and the absence of associated hemodynamically significant heart defects.

Exclusion Criteria

• Exclusion criteria were usual CMR contraindications such as ferromagnetic metallic implants.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

University of Leipzig - Heart Center; 🇩🇪 Leipzig, Germany